The adaptation of the lungs to air breathing at birth requires the fine orchestration of different processes to control lung morphogenesis and progenitor cell differentiation.However, there is little understanding of the role that epigenetic modifiers play in the control of lung development.We found that the histone methyl transferase Ezh2 plays a
Abstract Background Scimitar syndrome is a rare form of partial anomalous pulmonary venous drainage associated with pulmonary hypertension and congestive heart failure that may lead to death in the newborn infant.Although it is described with anomalies of the lung, heart and their vascular structure, extremely rei?llinen pizzalapio rare association
We have previously shown that plasma high density lipoproteins (HDL) stimulate release of prostacyclin, measured as its stable metabolite, 6-keto-PGF1 alpha, by cultured porcine aortic endothelial cells.The present experiments were designed to elucidate the contribution of HDL lipids to endothelial cellular phospholipid pools and to prostacyclin sy
Abstract Background Frailty and sarcopenia are common amongst hospitalised older people and associated with poor healthcare outcomes.Widely recognised tools for their identification are the Fried kk205 Frailty Phenotype, its self-report version the FRAIL Scale, and the European Working Group on Sarcopenia in Older People (EWGSOP) criteria.We studie